| MATCH | TIP | TIME | DATE |
|---|---|---|---|
| Celtic vs Hearts | FT:1 | 21:45 | 2021-12-02 |
| Casa Pia vs Varzim | FT:1 | 22:15 | 2021-12-02 |
| Ibiza Islas Pitiusas vs Tenerife | 2 | 23:00 | 2021-12-02 |
| Casa Pia vs Varzim | 1 | 23:15 | 2021-12-02 |
| Eldense vs Rayo Majadahonda | 2 | 22:30 | 2021-12-02 |
| Gaziantep vs Sakaryaspor | 1 | 21:00 | 2021-12-02 |
| Gernika vs Eibar | 2 | 21:00 | 2021-12-02 |
| Charleroi U21 vs Antwerp U21 | 1 | 21:30 | 2021-12-02 |
| AZ Alkmaar vs Sittard | 1 | 20:45 | 2021-12-02 |
| Velez vs Las Palmas | 2 | 18:00 | 2021-12-02 |
